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REDEFINE 2 — adults with type 2 diabetes GI events were reported in 72.5% of CagriSema participants vs 34.4% on placebo

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Notably, α-red myrrh may also exert indirect effects on fungal gene expression by modulating host signaling pathways such as NF-κB, p38, and JNK, which influence ERG6 regulation, suggesting a multifaceted mechanism of action (Jahanshiri et al., 2017)