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While the ability to proliferate and migrate uncontrollably is characteristic of tumor cells, glutamate has been shown to serve as a growth factor and signaling medium in certain types of tumor tissues in both an autocrine and paracrine manner (17)
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Nitro-FAs When the enzymatic production of superoxide (e.g., NADPH oxidases) and • NO occur in close proximity, these species can combine to form peroxynitrite, which can further react with carbon dioxide to yield • NO 2
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