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This occurs through increased expression of unphosphorylated signal transducer and activator of transcription 3 that induces renal proximal tubule cells to secrete the pro-inflammatory cytokine transforming growth factor β1 and the pro-inflammatory chemokine monocyte chemotactic protein 1

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10.1038/s41467-019-14190-2 56 LuY.WuD.WangX.WardS